Tigecycline Injection is an antibiotic formulation which is prescribed for treatment of various bacterial infections caused by Staphylococcus Aureus, E.coli, and Acinetobacter baumannii. Main active compound used in this injection is tigecycline having chemical formula C29H39N5O8 and molar mass of 585.65 g/mol. It works by blocking aminoacyl-tRNA interaction with A site of ribosome by binding to 30S subunit of ribosome.Tigecycline Injection is known to have excellent protein binding ability of 71 to 89% with elimination half-life of 42.4 hours.
Belongs to class of third generation tetracycline derivatives
Administered by intravenous route
Excreted from kidney and biliary system