Sterile Colistmethane Sodium Injection is specifically formulated to be used for treating chest infections in people suffering from cystic fibrosis. It has been formulated using colistimethate sodium as active compound. This is an antibiotic injection which shows effectiveness against various gram negative bacilli. This injection works by displacing magnesium & calcium ions present in lipopolysaccharide by interacting with outer membrane of bacteria. Sterile Colistmethane Sodium Injection is administered by intravenous route and is known to have elimination half life of about 5 hours.
It is a polycationic peptide
Have targeted mode of action
Can also be administered via intramuscular route